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Can Gene Therapy Help Fight Manic Depression

Those who suffer from bipolar disorder go through continuous bouts of mania and depression that affects them their entire life.

The cause of bipolar 1 disorder disease has been the focus of many studies but scientist may finally be getting closer to the crux of the problem.

For years, scientists have suspected a link between genes and manic depression. But there has been no peer studies to prove their point. But recent research points specifically to two genes that appear to play a dominant role in determining a person’s risk for developing manic depression.

If the discovery turns out to be true, it may potentially lead to a whole host of new and better treatments to combat the disorder.

The 2 genes that are responsible for all of the dreaded symptoms of manic depression are the ANK3 gene and the CACNA1C gene. The ANK3 gene is located on chromosome 10 at position q21. The CACNA1C gene is important in the production of the calcium channels which can be found in many of the body’s cells. These cells are particularly important to the operating of the heart and brain cells.

Furthermore, the proteins produced by these genes indirectly influence the activity in the brain’s nerve cells by controlling the flow of sodium and calcium in the brain.

And now that the researchers have a big clue as to the genes causing this disorder, they can begin to work on treatments that target the gene directly.

For further information on useful bipolar support groups and other bipolar issues, please visit Julie’s website.

Disclaimer: The medical info published on our website is in no way to be construed as a substitute for informed medical advice and you should not take any action before consulting with a health care professional.

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Pete in Articles on January 29 2010 » Comments are closed.